The Louis Family laboratory for targeted drug delivery & personalized medicine technologies
In our research group, we aim to improve patients' quality of life and treatment by developing innovative medical technologies. Specifically, we focus on targeted drug delivery systems to treat brain neurodegenerative diseases. Our nanotechnology is designed according to the loaded drug (proteins, gene delivery, and small molecules) and to the brain-targeting region. We also utilize our technology to treat various metastatic cancer types and inflammations and combine it with synthetic biology to develop artificial cells for therapeutic applications. Our lab is headed by Prof. Avi Schroeder, who has years of experience in nanotechnology and personalized medicine technologies.
Dr. Avi Schroeder has translational experience with the development of liposome-based clinical systems. He is the author of scientific papers in the field of nanotechnology and medicine. Schroeder is the inventor on 19 patents, and recipient of 30 national and international innovation awards. Dr. Schroeder is a scientific-entrepreneur, starting 5 successful Technion spin-outs
Our research is supported by:
Phospholipids Research Center
Israel Innovation Authority
Israel Science Foundation - ISF
Years of Experience
Avi received all three degrees in Chemical Engineering from the Ben-Gurion University. His postdoctoral training at the Massachusetts Institute of Technology (2012). At MIT, Avi and colleagues developed nanoparticles that are capable of autonomously synthesizing proteins upon signal, thereby being a platform for on-site delivery of drugs and preventing damage to healthy organs. In our lab, Avi is building an expert team to work towards improved personalized and targeted medicine.
Janna received her B.Sc. in Biotechnology and Food Engineering from the Technion-Israel Institute of Technology (2007)... She completed her PhD studies under the supervision of Prof. Ayelet Fishman in the same department. Her research focused on production of valuable chiral sulfoxides using oxidizing enzymes. Janna joined Dr. Schroeder’s group and serves as a lab director and senior scientist, involved in many projects in the lab.
Jeny received BA, MSc and PhD from the Technion. During her PhD obtained under the supervision of Dr. Estee Kurant, she focused on processes involved in dead cells removal at the embryonic central nervous system. In her postdoc at Griffiths lab in UCDAVIS she investigated different aspects of endothelial cells recellularization of xenogeneic scaffolds and development of a novel antigen removal method. Jeny joined Schroeder group in 2019 and serves as lab manager and senior scientist.
Hanan graduated from the Hebrew University with a MSc in Pharmaceutical Sciences, gaining two Excellence Awards for her work. Hanan is completing her PhD in our group, focusing on targeting the tumor microenvironment with nanotechnology.
Omer received his BSc in biochemical engineering at the Technion (2017). Omer worked as an undergraduate research student in the lab for 3 years focusing on proteolytic enzyme delivery for tissue manipulation. In his current PhD research, Omer is focusing on development of synthetic cells and cell-free protein synthesis systems.
Maria Poley is a Ph.D. candidate in Prof. Schroeder's laboratory. She earned her B.Sc. degree in biochemical engineering from the Technion - Israel institute of technology. She has two main research focuses. The first is the effect of nanotechnology on the female reproductive system and fertility, and the second is targeted drug delivery to treat Parkinson's disease.
Mohammed received his B.Sc in pharmaceutical engineering from Azrieli college of engineering (2014). He completed his MSc studies under the supervision of Prof. Avi Domb at the Hebrew University in Medicinal Chemistry (2017). Mohammed is completing his PhD studies in our group, focusing on active targeting of Head and neck cancer using nanotechnology.
Maya received her B.Sc. in Biotechnology and Food Engineering from the Technion (2017). Maya joined our lab in August 2015, and together with Dr. Krinsky developed synthetic cells for onsite therapeutic protein production. Her current PhD research combines the field of nanotechnology, neurobiology and cancer therapy. Maya developed nanotechnology that targets the tumors neurons as a tool for treating metastatic breast cancer.
Gal received her B.Sc in biochemical engineering from Technion in 2018. She joined the Schroeder’s lab as an undergraduate student in 2017 and participated in developing the synthetic cell system. Today, she is an Arian de Rothschild P.hD. fellow. Her research focuses on engineering artificial cells for regenerative medicine applications
Aviram received his B.Sc. in Biochemical Engineering from the Technion (2018). Aviram started working at the lab in March 2018 as a part of collaboration with a lab from the Hebrew University. Aviram’s current study focuses on developing new generation of RNA delivery systems.
Mor received her B.Sc. in Chemistry from the Ben-Gurion University of the Negev (2018). Mor joined the lab in October 2019, and together with Maya Kaduri (PhD student) developed a nanodrug delivery system for targeting neurons at the breast tumor microenvironment. In her current PhD research, Mor is focusing on developing active targeting nanoparticles to the brain for treating neurodegenerative diseases, specifically Parkinson's disease.
Noga received her B.Sc in Biochemical Engineering at the Technion (2016). Noga has been working for 3 years as R&D engineer in NanoSpun Technologies and has joined the team in February 2019. In her current M.Sc research, Noga is focusing on designing synthetic cells system as a base for therapeutic applications.
Ravit recived her B.Sc in Chemical engineering from the technion (2021). Ravit joined the team in 2018 as an undergraduate research student, focusing on synthetic cells and cell-free protein synthesis system. In her current research, she is developing a photocatalytic nano particles for therapiutic applications.
Egor received his integrated BSc and MSc degree in Medical Biochemistry at The University of Manchester (2019). He completed his MSc studies under the supervision of Prof. Stephen Taylor at the MCRC, The University of Manchester (2019). Egor joined the lab in January 2020 and is currently studying towards an MSc degree in Nanotechnology. Egor's work is centred on the creation of liposomal and polymeric formulations for DNA and RNA delivery to cells using manual and automated approaches.